Born Edilberta Angelillo in Venice, she is the daughter of singers and stage artists who performed with the name Franco & Regina.
[1] Angelillo studied dance, mime and acting, and at 19 years old, in 1979, she made her film debut in Maurizio Nichetti's Ratataplan.
[1] The same year, Angelillo debuted on television as an assistant in Rai 1 variety show Domenica in, and recorded her first single as a singer.
[1] In 1981, she acted in theatre the play La vita comincia ogni mattina, with Gino Bramieri.
[1] In 1997 she was nominated to the David di Donatello for best supporting actress thanks to her performance in La bruttina stagionata.