[2] Lederer worked with Jean Heller at the Associated Press (AP) New York City headquarters at 50 Rockefeller Plaza.

[3] In 1968, while working at the AP's San Francisco bureau, Lederer met Peter Buxtun and he spoke to her about his ethical concerns regarding the Tuskegee Syphilis Study.

Lederer recognized the newsworthiness of the information and passed it on to a colleague, Associated Press investigative reporter Jean Heller, who broke the story, resulting in the ending of the study.

[3] Lederer was the first female resident correspondent in Vietnam[4] in 1971[2] and the first woman to head a foreign bureau for the AP,[5] in Lima, Peru in 1975.

[6] She worked for the AP for five decades, becoming the chief correspondent at the United Nations.