[3] Mitchell subsequently completed her internship and residency in internal medicine at Meharry Medical College and became a hematologist at the Andrews Air Force Base.

There, she conducted research into pancreatic cancer which involved new drug evaluation and chemotherapy, development of new therapeutic regimens, chemoradiation strategies for combined modality therapy, and patient selection criteria.

[12] Mitchell also received the National Medical Association Council on Concerns of Women Physicians Pfizer Research Award for her "outstanding contributions to clinical or academic medicine.

[17] Mitchell earned the 2012 American Society of Clinical Oncology Humanitarian Award for providing patient care "through innovative means or exceptional service or leadership in the United States or abroad.

[21] During the fall, Mitchell presented advice and opinions about what Congress can do to increase African American health care, funds, and research during the legislative conference of the Congressional Black Caucus.

[24] Mitchell also created patient education videos about the screening and treatment of colorectal and breast cancers which was televised during Black History Month and later distributed to doctors’ offices across the United States.