Seuil has published works by Jacques Lacan, Roland Barthes and Philippe Sollers (in his first period), and later by Edgar Morin, Maurice Genevoix and Pierre Bourdieu.

Notably, they published Frantz Fanon's doctoral thesis, Black Skin, White Masks, in 1952, and the first edition of Aleksandr Solzhenitsyn's The Gulag Archipelago (in Russian as Архипелаг ГУЛАГ) in 1973.

Similarly, Seuil's good relations with book retailers have allowed it to establish significant distribution activity, ensuring the circulation of the works of such publishers as Odile Jacob, Éditions de Minuit, José Corti, and Rivages.

The house has promoted and published many great French children's authors; in 2005 Éditions du Seuil was the first to offer to the public animated films included in their albums that were produced by the artists themselves, such as À Quai by Sara and Promenade d'un distrait, by Béatrice Alemagna.

To the books of Paul Celan [...], Perec, Vernant, Pastoureau, Borges, Rancière, Tabucchi, Lydia Flem, Starobinski [...] are added the works of [...] Yves Bonnefoy, Pascal Dusapin and the final novel of François Maspero.