He followed on the spot, for his master, the decoration work and the creation of the furniture from 1864 until the fall of Napoleon III in 1870, when, for lack of money, the building site stopped.

[4] During his adolescent travels to southern Spain, in North Africa and the Middle-east, Edmond Duthoit discovered Moorish art.

Charged with a mission in the Orient, he accompanied, between 1861 and 1863, in Syria and Cyprus, the count Melchior de Vogüé, with whom he collaborated for the publication l'Architecture civile et religieuse du ier au viie siècle en Syrie, thus the name of the room of Cypriot antiquities in the Louvre: Vogüé-Duthoit.

He was tasked by the French government to arbiter a conflict that opposed in 1872, the municipality of Tlemcen and the population, concerning urban development near the great mosque of the city.

From 1884 onwards, he completed his masterpiece, the Notre-Dame basilisk of Brebières at Albert in the Somme, a majestic monument inspired by both Byzantine and Moorish art, where we can spot the influence of fellow architect Léon Vaudoyer.