About 18 months after the (mid-school-year) opening of the new junior high, Hurricane Betsy struck as the 1965-66 school year was starting.

When school restarted, physical education classes were held outdoors until the floor had been replaced.

As a result, significant changes took place: upper grade levels, new courses, and high school traditions were added.

Edna Karr reopened as a senior high charter school serving grades 9 through 12.

[6] State Championships (7) Football: 1993, 2012, 2016, 2017, 2018, 2019, 2024 (8) Track (Boys & Girls) 1996, 2003, 2013, 2015, 2016, 2017, 2018, 2019 Edna Karr's marching band is known as "#TeamBustEmUp" and includes 100+ instrumentalists, dancers (Cougar Dolls), a flag corp, and twirlers.

Some notable accomplishments of the band include being highlighted in a documentary on New Orleans, photographed for ESPN's 10th Anniversary of Hurricane Katrina issue, invited to perform in London, England for the city's 2016 New Years Day Parade, and a cameo appearance in Beyoncé's Lemonade visual album.