He is also considered an integral part to the "Armenian School" of music composition alongside the composers Arno Babajanian and Alexander Arutiunian.
His mother was an actress of the Sundukyan Theater and had trained at Yerevan Conservatory in classical singing, although did not choose to pursue a career.
Mirzoyan's compositional output is relatively small but quite distinguished, combining graceful lyricism with intense drama.
With its formal structure and tonal design, his style has been described as Neoclassical, with elements of Armenian folksong always present.
Edvard Mirzoyan died on October 5 of 2012, and is buried at the Komitas Pantheon which is located in the city center of Yerevan.