Sir Edward Leigh (24 March 1602 – 2 June 1671) was an English lay writer, known particularly for his works on religious topics, and a politician who sat in the House of Commons from 1645 to 1648.

At the outbreak of civil war, Leigh upon being appointed colonel in the Parliamentary Army preferred not to be styled Sir.

On 30 September 1644 he presented to parliament a petition from Staffordshire Parliamentarians complaining of Cavalier oppression, and made a speech which was printed.

A Latin translation by Henricus à Middoch, accompanied with observations on all the Chaldee words of the Old Testament by J. Hesser, was issued at Amsterdam, 3rd edit., 1696; 5th edit, with appendix by J. C. Kesler, Gotha, 1706.

He also published Christopher Cartwright's The Magistrate's Authority in matters of Religion, 1647, to which he prefixed a preface in defence of his conduct for sitting in the Westminster Assembly of Divines and other clerical meetings.

He assisted William Hinde in bringing out John Rainolds's The Prophesie of Haggai interpreted and applyed, 1649; and edited by himself Lancelot Andrewes's Discourse of Ceremonies, 1653.