Edward Nettleship FRS FCS (3 March 1845 – 30 October 1913) was an English ophthalmologist.

After finishing his medical studies at King's College London, Nettleship became an assistant to Jonathan Hutchinson (1828–1913) at the London Hospital, and a coworker with Warren Tay (1843–1927) at the Moorfields Eye Hospital.

Later, he spent nearly twenty years at St. Thomas Hospital in London, where he was mentor to Charles Howard Usher (1865–1942).

He made important contributions in the research of ocular albinism, retinitis pigmentosa and hereditary night blindness.

Prior to specializing in ophthalmology, Nettleship studied veterinary medicine and dermatology, and in 1869 provided an early description of urticaria pigmentosa.