Edward Octavius Sisson (1869–1949) was an American classicist, historian, philosopher and university administrator.

He was born on May 24, 1869 in Gateshead, Durham to George Sisson and Mary Arnott.

[1] He married Astid Honoria,[2] with whom he had a son Richard Alvin Sisson.

[4] He served as teacher and principal of public schools from 1886 to 1891.

[4] He served as one of the Presidents of the University of Montana from September 1917 to August 1921.