Edward Sydney Simpson (11 March 1875 – 30 August 1939) was an Australian mineralogist and geochemist.
Simpson was born in Woollahra, New South Wales to an Irish father and English mother.
Simpson worked at the Rivertree silver mill, New South Wales and then for the Mount Morgan Gold-Mining Company in Queensland.
Simpson was a founder of the Natural History and Science Society of Western Australia and its successor, the Royal Society of Western Australia which awarded him the Kelvin Medal in 1929.
He was awarded the Clarke Medal by the Royal Society of New South Wales in 1934.