Edwin Ernesto Portillo (born November 17, 1962, in Metapán) is a former Salvadoran professional footballer and current manager.
In February 2014, Portillo signed as new coach of Águila, replacing Raúl Martínez Sambulá for the rest of the Clausura 2014.
In October 2015, Portillo signed as new coach of Sonsonate for the rest of the Apertura 2015, replacing Héctor Jara.
In December 2018, it was announced that Agustín Castillo would be replaced by Portillo as new coach of Isidro Metapán for the Clausura 2019.
Edwin Portillo's Isidro Metapán became the first Salvadoran team to qualify for the quarter-finals (last eight) in the CONCACAF Champions League new format.