Effie Kapsalis (April 21, 1971 – December 11, 2022) was an American open access advocate known for work related to digital programs and initiatives, including those advanced at the Smithsonian Institution.

She went on to earn a master's degree from the University of the Arts (Philadelphia) in industrial design and pervasive technology.

[1] As senior digital program officer at the Smithsonian, Kapsalis headed the team responsible for making 2.8 million high-resolution two- and three-dimensional images from the institute's collections openly available online in 2020.

[2][3][4] She worked to make the Smithsonian's archival collections more accessible online and authored a blog series titled Wonderful Women Wednesday.

[6] In 2013 Kapsalis and Sara Snyder were the recipients of the inaugural Distinguished Service Award by the Wikimedia District of Columbia for their work within the Smithsonian Institution encouraging people to learn how to edit Wikipedia.