Established in 1945, Ehime Prefectural Uwajima Fisheries High School has produced a large number of alumni.

The school is the only fishery high school in Ehime Prefecture in Uwajima-shi, an area known for its production of Pagrus aquaculture and pearl aquaculture.

The school operated the vessel Ehime Maru (4th generation), which the USS Greenville, a U.S. Navy submarine, struck and sank on February 9, 2001 during the Ehime Maru and USS Greeneville collision.

The school acquired a new Ehime Maru (5th generation) ship with settlement money from the U.S. Navy.

In Hawaii, the principal at the time of the disaster, Kazumitsu Joko (上甲 一光 Jōkō Kazumitsu), read a message from Moriyuki Kato (加戸 守行 Kato Moriyuki), the governor of Ehime Prefecture, addressed to the Hawaiian people.