[7][8][9][10][11] She is also known for portraying Polly Renfrew in the CBBC TV adaptation of Jacqueline Wilson's Hetty Feather and Cait in the Sky Atlantic series Britannia.

[14] Before starring in Matilda, Worthington Cox was in the chorus for a Bill Kenwright production of Joseph and the Amazing Technicolor Dreamcoat at the Liverpool Empire.

[2][18] Worthington Cox continued to appear in Matilda until 19 August 2012, later sharing the role with Demetriou, Hayley Canham, Jade Marner, and Isobelle Molloy.

[14] In May 2013, Worthington Cox played Scout in a stage production of To Kill a Mockingbird at Regent's Park Open Air Theatre,[19] sharing her role with Lucy Hutchinson and Izzy Lee.

[10][11] She was also featured as one of Screen International's "Stars of Tomorrow", the film magazine's annual showcase highlighting outstanding young actors from the UK and Ireland.