Elise Depew Strang L'Esperance (1878–1958) was an American pathologist and physician, a pioneer in establishing a preventive model of cancer treatment.

[1] She was a pathologist noted for establishing cancer prevention clinics in New York.

Inspired by her father, she pursued a career in medicine and attended the Woman's Medical College of the New York Infirmary for Women and Children, earning her M.D.

Interested in pediatrics, L'Esperance spent a year working at Babies Hospital in New York.

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