Elizabeth Cheney (referred to as Lady Say; April 1422 – 25 September 1473) was a member of the English gentry, who was the great-grandmother of Anne Boleyn, Jane Seymour, and Catherine Howard, three of the wives of King Henry VIII of England, thus making her great-great-grandmother to King Edward VI, the son of Henry VIII and Jane Seymour, and Elizabeth I, the daughter of Henry VIII and Anne Boleyn.

[citation needed] On an unknown date, Elizabeth Cheney married her first husband Sir Frederick Tilney, of Ashwellthorpe, Norfolk, and Boston, Lincolnshire.

Shortly before 1 December 1446, Elizabeth Cheney married secondly Sir John Say, of Broxbourne, Hertfordshire, Speaker of the House of Commons, and a member of the household of King Henry VI.

[2] Her father settled land worth fifty marks clear per annum upon the couple and their issue before Candlemas, 1453.

Sometime after 1478, Elizabeth's eldest son, Sir William Say, married his second wife, Elizabeth Fray, a daughter of his stepmother Agnes, by her first husband, Sir John Fray (1419–1461), Chief Baron of the Exchequer.