Elizabeth Dickinson Getzoff is an American biochemist.
She holds a joint appointment at Scripps Research Institute in California, as professor emeritus in immunology and Microbiology, as well as integrative structural and computational biology (ISCB)[1] Getzoff received her chemistry degree at Duke University in 1976, where she also completed her doctoral studies in biochemistry in 1982.
[3] The main focus of her team is the characterization of protein conformational changes in cellular pathways, such as protein recognition, interaction and catalysis.
In particular, they are interested in proteins involved in photosensing, in the enzymatic control of reactive oxygen and nitrogen species, in the coupling of metal-site chemistry and electron transfer for catalysis, and in protein networks involved in circadian rhythms.
In their studies, they use multidisciplinary approaches that include high-resolution protein crystallography, computational and computer graphics analysis, protein design cycles, small angle X-ray scattering, biochemical and spectroscopic analyses, and further molecular biology techniques[4] Her most cited publications are