Elizabeth, Marchioness of Lothian (née Fortescue; 3 April 1745 – 30 September 1780) was a noblewoman in the peerage of Great Britain and Ireland.
She was a daughter of Chichester Fortescue (1718–1757), High Sheriff of County Down in what is now Northern Ireland.
On 15 July 1762, she married William John Kerr (1737-1815), who was then styled Lord Newbottle or Newbattle and Earl of Ancram.
After the death of Kerr's father in 1775, he inherited the Marquisate of Lothian, making Elizabeth a marchioness by marriage.
He and Elizabeth Kerr had nine children, the last of which was Lord Robert Kerr, born on 14 September 1780.