She made her Broadway debut in the Roundabout Theatre Company's revival of the Tennessee Williams play The Rose Tattoo (2019).

Rubin made her Broadway debut in the 2019 revival of The Rose Tattoo starring opposite Tomei.

[11] She played Natalie Gibson in the Hulu limited series The Girl from Plainville (2022) starring Elle Fanning.

[12] In 2023, she acted in the coming-of-age surrealist comedy The Sweet East directed by Sean Price Williams.

[13] In 2024, she had a supporting role in the Anne Hathaway-led romantic comedy The Idea of You on Prime Video[14] and played Vera in Sean Baker's film Anora starring Mikey Madison.