[1][2][3] She co-organized a National Day of Action in 2015 to bring attention to the black trans women who were killed that year.

[6] In 2015, Moxley was one of the organizers of The Movement for Black Lives, a national three-day conference in Cleveland, Ohio.

[2] Her writings have been featured in publications including the City University of New York Law Review and Ebony.

[16][17] In February 2017, Moxley, along with other trans activists, criticized the pussyhat that had become a symbol of the 2017 Women's March, stating that the movement needs to be truly intersectional and consider the "anatomy of all people".

Comedian Lil Duval joked about killing a sex partner if she turned out to be transgender, and host Charlamagne Tha God, while noting that killing a trans person was a hate crime, stated that women not disclosing their trans status were "taking away a person's power of choice" and "should go to jail or something".