Perez made her Grand Slam main-draw debut at the 2016 Australian Open in doubles with Belinda Woolcock; they lost in the first round to Jessica Moore and Storm Sanders.

[2] Perez made her debut on the ITF Women's Circuit in March 2012 in Bundaberg, losing in three sets to Jennifer Elie.

In 2014, Perez reached the quarterfinal of the Burnie International and Melbourne, and then competed on the ITF Circuit in Europe until June when she started attending college in the United States.

In June 2015, Perez returned to play at Bethany Beach where she qualified and reached the singles quarterfinals and the doubles final.

Perez said of the experience "It definitely didn't go as planned, or as hoped, but it was great to be able to have my Grand Slam debut and get out on court in front of all the fans and what-not.

Perez began the season with a wildcard into the Sydney International qualifying where she defeated Kateryna Kozlova, ranked 101 in the world.

In September, she attempted to qualify for two WTA tournaments in Asia before returning to Australia in October where she reached four consecutive ITF finals.

[citation needed] In March, she won the Abierto Zapopan in doubles with Astra Sharma, it was her second WTA Tour title.

[citation needed] In July, Perez partnered Samantha Stosur in women's doubles at the 2020 Olympic Games, where they reached the quarterfinals.

At the French Open, with Nicole Melichar-Martinez, Perez reached the quarterfinals for the first time, having never previously progressed beyond the second round at this major.

[14] With her win over protected ranking pair of Sara Sorribes Tormo and Marie Bouzková, she became the 21st Australian woman to advance to a Roland Garros semifinal in doubles in the Open Era.

[18] As top seeds, they won the 2024 Bad Homburg Open, defeating Chan Hao-ching and Veronika Kudermetova in the final.

[19] Perez and Melichar-Martinez qualified for the 2024 WTA Finals and reached the semifinals after compiling a record of two wins and one loss in the group stages.

[22] Only main-draw results in WTA Tour, Grand Slam tournaments, Fed Cup/Billie Jean King Cup and Olympic Games are included in win–loss records.