Born in Reading, Pennsylvania, but raised in New Haven, Connecticut, Ayala took up boxing as a way to stay off the streets and out of trouble.

"[1] At the age of 22, Ayala made his professional debut on September 19, 2003, with a unanimous decision win over Michael Gutrick in Toms River, New Jersey, a short distance from his hometown of Reading, Pennsylvania.

On November 11, 2004, Ayala earned his eighth professional win by knocking out Chance Leggett, then 11–3, in the seventh round of a scheduled eight-round bout at The Roxy in Boston, Massachusetts.

Ayala eventually won his first 16 fights before facing his toughest test to date against future The Contender reality television participant David Banks, who was 12-1-1 at the time, on November 24, 2006, at The Roxy.

[2] Ayala bounced back with back-to-back wins against Dillon Carew and Jose Angel Roman in Connecticut and closed the year with arguably his most impressive performance in a controversial draw against then-unbeaten The Contender Season 1 champion Sergio Mora at the Home Depot Center in Carson, California.

[3] Following a 10-month stretch of inactivity, Ayala returned with back-to-back wins against Antony Bartinelli and Eddie Caminero before losing a United States Boxing Association (USBA) middleweight title bout against former world-title challenger Lajuan Simon by unanimous decision at the Palms Casino Resort.

Ayala then traveled to Montreal, Quebec in June 2010 to face hometown favorite David Lemieux, who entered the bout at 22–0 with 21 knockouts, on ESPN's Friday Night Fights for the WBC International middleweight title.