The chancery is located at 2650 Wisconsin Avenue, Northwest, Washington, D.C.[1][2] The embassy oversees consulates in New York and Houston.

Built in 1910, this Beaux-Arts mansion served variously as the Russian or Soviet embassy during periods of established relations between 1913 and 1994.

Under the 1972 agreement, equivalent territory in Moscow was to be leased to the United States for a new embassy on the same conditions.

In 1985, Vitaly Yurchenko redefected here, after eluding his handlers at the Au Pied de Cochon restaurant in Georgetown.

[7][8][9] On February 27, 2018, a one-block section of Wisconsin Avenue in front of the embassy was renamed Boris Nemtsov Plaza in honor of Boris Nemtsov, an opposition activist and vocal critic of Russian President Vladimir Putin who was shot dead by assassins while walking on a bridge near the Kremlin on February 27, 2015.