On April 18, 2022, the embassy in Bogota started allowing U.S. citizens located in Venezuela to renew their passports by mail, thus restoring access to some consular services.

On 1958, shortly after the overthrow of Venezuelan dictator Marcos Pérez Jiménez, Vice President of the United States Richard Nixon's motorcade was attacked in Caracas during his 1958 goodwill tour of South America.

[1] In Nixon's remembrance of the incident, Associated Press photographer Hank Griffin at one point had to use his camera to beat back a protester who tried to mount the truck.

[2] According to a second account, soldiers of the Venezuelan Army arrived and cleared the traffic, thereafter moving the mob back at bayonet-point to allow Nixon's car to pass.

[12] In December 2017, Todd D. Robinson was appointed by President Donald Trump to be charge d'affairs en pied at the embassy in Caracas, Venezuela.

In January 2018, Robinson attempted to obtain the release of American citizen, Joshua Holt who had been jailed in the country by meeting with Venezuelan foreign minister, Jorge Arreaza.

[13] On 22 May the same year, Robinson and his deputy, Brian Naranjo were expelled from the country as persona non grata by Nicolas Maduro, the newly re-elected president.

[16] On 12 March 2019, Secretary of State Mike Pompeo announced over Twitter that the US would withdraw all remaining personnel from the embassy within the week, citing the increasingly deteriorating situation in the country.