Since the inception of diplomatic ties in 1962, Trinidad and Tobago has become one of the most industrialized nations in the English-speaking Caribbean.

[2] On August 31, 1962, the United States recognized the newly independent Trinidad and Tobago and established the U.S. Embassy in Port of Spain the same day.

Judge William Henry Hastie, serving on the U.S. Court of Appeals for the Third Circuit, led the U.S. delegation at the independence ceremonies.

[3] William H. Christensen was the first to hold the position as chargé d'affaires ad interim at the embassy.

[4][5] On April 27, 2022, US Embassy officials and National Trust of Trinidad and Tobago officials visited the site of Trinidad Country Club in Maraval, drawing speculation that the US Embassy would buy the property.