[4] The left back did not break into the first-team at La Bombonera when he caught the attention of scouts Frank McParland and Paddy Murphy from Liverpool.
[17] Insúa made his debut for Sporting on 15 September 2011 in the UEFA Europa League, scoring the first goal in a 2–0 victory over FC Zurich.
[19] On 25 January 2013, Atlético Madrid announced that they have reached an agreement with Sporting Clube de Portugal for the transfer of Insúa,[20] reportedly for €3.5 million.
[26] On 14 February 2021, Insúa agreed his return to Argentina after nearly 14 years abroad, joining Aldosivi in the Primera División on a free transfer and a deal running until December.
[28] The player succeeded on the Under-20s international scene, playing three games to finish with the runner-up medal at the 2007 South American Youth Championship, which served as a qualifier for the FIFA U20 World Cup where he played seven games, conceding just 4 goals in the entire tournament and aiding the Argentina Under-20 team to victory against the Czech Republic in the FIFA U20 World Cup final on 22 July 2007.
[29] On 24 August 2009, Liverpool manager Rafael Benítez said that Diego Maradona was monitoring the progress of Insúa and considering calling him up for international duty with Argentina.
[31] Liverpool Atlético Madrid VfB Stuttgart Racing Club Argentina Insúa's younger brother, Emanuel, is also a footballer and left back.