In April 1911 he led the forces which conquered the Mexican state of Durango, capturing Mapimí, Lerdo, and Gómez Palacio.

[1][7] The couple had four children,[7] including Pablo Emilio Madero Belden,[8] who was inspired to go into politics on his father's account.

[10][11] Following the death of his brother Francisco, it was reported that he had been shot and killed just north of Monterrey on 26 February; according to rumor he had been overtaken by General Treviño between Villaldama and Bustamante while leading a group of 35 to join a force of rebels in Laredo.

[12][13][14] On 6 March, he was forced to flee Mexico with another brother, General Raúl Madero, and the two swore to avenge the President's death.

[22] Madero died in Mexico City on 16 January 1962,[1] and was buried in the Panteón Francés de la Piedad.