The order had been invited to establish this Catholic Secondary Boys' College by the then Archbishop of Melbourne, Daniel Mannix.

The college's colours were then red, white and blue and its motto was Ecce Mater Tua (Latin: "Behold Thy Mother").

In the early 1960s, the local parish priests purchased a large, 9-hectare, undeveloped block in Altona North.

In 2004, with the assistance of a Commonwealth Government grant, work commenced on enlarging the library complex and the building of two new computer labs.

These were the expansion of the Technology Building, construction of a new canteen, gym, changing rooms and toilets and the new McMahon Language Centre.

Since 2023, the current principal is Dr. Janine Biggin who "strives for excellence as a Catholic educator and school leader."