[2] He transferred to South African National First Division team Mpumalanga Black Aces in January 2008 and debuted against Dynamos F.C.

[5] Emenike won the 1.Lig Best Foreign Player award at the end of the 2009–10 season,[6] and also had his contract extended by three years for 300.000 €.

[9][10] On 28 July 2011, he was sold to Spartak Moscow for €10 million due to the match fixing claim, which was disproven by the court later on,[11] involving Fenerbahce and Emenike.

Emenike made his debut on the opening game of the season coming on as a substitute for Ari in the 76th minute, against Anzhi Makhachkala on 14 August 2011.

Emenike made his Europa League debut in a 2–2 draw against Polish side Legia Warsaw in the first leg of the qualification round.

Vladimir Vasilyev, a Russian FA's ethics committee official, explained the fine, stating it was "an adequate punishment".

After the match, Nigerian teammate Efe Ambrose spoke to Goal.com praising Emenike for his "electrifying performance"[20] But in the second half of the season, his playing time was reduced, due to injuries.

On 31 January 2016, Emenike signed for West Ham United on loan until the end of the season with an option to make it permanent.

[26] On 21 February, Emenike scored a brace in a 5–1 win against Blackburn Rovers in the FA Cup, his first and only goals for the club.

[28][29] On 25 July 2017, Emenike made his first appearance for the club, scoring a last minute goal, helping Olympiacos to a 3–1 victory against FK Partizan, in the 1st leg of the UEFA Champions League third qualifying round.

[30][31] On 19 September 2017, thanks to a brace scored by Emenike at second half, Olympiacos won 2–1 against Asteras Tripoli, at this 2017-18 Greek Cup clash, at Georgios Karaiskakis Stadium.

[32] In November 2017 Emenike was reportedly under orders to train alone even though he was not recovering from any injury and was linked with a move away from Olympiacos with CSKA Moscow mentioned as a possible destination.

Emenike had complained of being unsafe at his home in Greece and Olympiacos were forced to hire extra security to protect him.

[33][34][35] On 29 December 2017, Emenike thanked Turkish giants Galatasaray for their brave step in reaching out to embattled former Arsenal and Ivorian defender, Emmanuel Eboue, who lost a bitter divorce battle, with his wife Aurelie awarded all of their assets, had to hide from cops and bailiffs after being ordered by a judge to transfer his remaining Enfield home in England to his wife.

[38] Few days after his signing the Spanish club have announced that Emenike is now being treated for a knee problem and no date was fixed for his return to action.

On 3 February, Emenike scored a 30-yard free kick giving his country a 2–1 win over Côte d'Ivoire in the African Cup of Nations.

[54] He came on as a substitute three days later in a friendly match against Burkina Faso, played in Kaduna – he scored the fourth goal in a 4–1 win for the Eagles.