He belongs to the elite group of Greek painters that followed the Venetian influenced maniera greca in Crete.

He is one of few artists to not travel to the Ionian Islands and participate in the Heptanese School.

Christodoulos Kalergis is another prominent Greek artist associated with the Cyclades, he was from Mykonos.

Skordilis was influenced by Georgios Klontzas, Michael Damaskinos and Angelos.

Cretan priest and painter Antonios Skordilis was also associated with the island Mylos.

Skordilis painted his own version of the historic In Thee Rejoiceth.