A unique inscription on a holy table at the church of Agios Spyridon in Kefalonia features important details about his life.

[1] Paintings of the Virgin Mary and child Jesus were extremely common in Greek-Italian Byzantine art.

Famous Greek painter Angelos Akotantos created many works in the style.

Tzangarola's painting Virgin Glykofilousa with the Akathist Hymn is very similar to Karadinos's work.

Tzangarola and Karadinos may have copied an existing work that was on the island of Kefalonia around their time.

The original painting did not survive but historical documents name the work of art.

It is part of the collection of the Kimisis Church of Panagia Sami (Κοίμησης της Παναγίας στη Σάμη).

[3][4] The work of art is made of egg tempera paint and gold leaf on a wood panel.

The luxuriant patterns and folds of fabric reflect the advancement of both Cretan Renaissance and Heptanese painting styles.

The work strongly resembles Tzangarola's Virgin Glykofilousa with the Akathist Hymn.

In Karadinos's painting the Virgin and Child both have accentuated curved facial features.

The Greek writing is as follows: Servant of God Bernardo (Venardos) Aninos, while in the village Komitata a part of Eriso while sitting in his house, at the sixth hour of the day, a thunderbolt suddenly fell from the sky and killed him he was age 35 in the month of January 24, 1723 (Δούλος τον Θεοϋ βενάρδος ο άνινος ών έν χωρίω Κομιτάτα μέρος Έρίσου έν τώ οϊκω αύτού καθεζόμενος ώρα έκτη τής ημέρας κεραυνός εξαίφνης πεσών εκ τού ουρανού κατέφλεξε και / έθανάτοσεν αυτόν εν έτει τής ήλικίας αυτού 35 έν μηνί Ιανουαρίου 24, 1723).

The small inscription on the bottom of the work assisted historians in retracing the origin of the icon.

The event took place inside Bernardο's house, in the village of Komitata, located on the west side of the Erissos peninsula, in the northern part of Kefalonia.

In 1736, an abbot named Raphael Aninos commissioned a work that is nearly identical to the Virgin Glykofilousa.

Around this period Karadinos also taught painting to a prominent member of the noble family named Athanasios Aninos (1713-1748).