After Crystal Palace failed to gain promotion, Boyce returned to Premier League football in 2006, this time with Wigan Athletic F.C.

after completing a move for a fee of £1 million, and was a key player during his first season when the club narrowly avoided relegation.

He remained an active member of the first-team throughout his spell at Wigan, and is the club's Premier League appearance record holder.

He grew up in Elmhurst with his parents, Lucille and Melvin,[4] and attended Quarrendon CE Secondary School,[5] where he set athletics records.

[9] He signed professional terms with the club in 1998, and made his debut on 5 January 1999 in a 3–0 home defeat against Walsall in the Football League Trophy.

[9] He kept his place in the starting lineup and played 30 times in the league during the season, and scored his first goal for the club in a 2–1 defeat against Bournemouth in February 2000.

New Luton manager Ricky Hill praised Boyce for his "tremendous" displays,[12] and felt he deserved a call-up to the England under-21 squad.

Boyce was a key figure in the following season for Luton as they gained promotion back into the Second Division, and he was rewarded with a new two-year contract.

[8] Following a short trial,[16] Boyce moved to Crystal Palace in July 2004 on a free transfer, signing a two-year deal with the club.

[25] With 12 months remaining on his current contract, Boyce rejected a new deal with Palace, stating his desire to return to the Premier League.

[26] Rather than letting him leave for free at the end of his contract per the Bosman ruling, Palace accepted an offer for Boyce from Wigan Athletic.

[31] His performances earned him praise from Wigan supporters, and he narrowly missed out on the club's Player of the Year award.

[32] At the start of the 2007–08 season, following the signing of Mario Melchiot as the club's new first choice right-back, Boyce found his first team opportunities more limited.

[34] Replays showed that the decision was harsh, and Wigan manager Steve Bruce called for rule changes to allow clubs to appeal against yellow cards, and also to introduce video technology.

[35] Two weeks later, on 29 November 2008, he scored his first goal for Wigan, a header from the edge of the area in a 2–1 win against West Bromwich Albion.

Under new manager Roberto Martínez, he was initially part of the starting line-up, but after being replaced by new signing Gary Caldwell in January, his playing time became more limited.

[40] He appeared 22 times in the league, and started in the final game of the season against Stoke City, making a goal line clearance in the first half to keep the score level.

[46] In March 2014, he was once again instrumental in captaining Wigan to an upset over Manchester City, this time in the 2014 FA Cup Quarterfinals.

[48] In August 2020 Boyce came out of retirement to sign for Ashton Town FC after an invitation from chairman Mark Hayes.

On his new role, Boyce commented that "Soccer is a global sport, it can lift all of our spirits and improve all of our lives and I want to promote the use of the beautiful game in this way.