Marquez then appeared in TV5's Lokomoko (2008–2013), Tropa Mo Ko Unli (2013–2015), and played the titular superhero character in Kapitan Awesome (2012–2013).

[9] He then played the titular superhero character in Kapitan Awesome (2012–2013), and became a cast member of Tropa Mo Ko Unli (2013–2015).

He portrayed Tonyo, a plain-looking but kind-hearted OFW in Japan, who falls in love with a blind woman played by De Rossi.

[20][21] Due to the film's popularity, the entertainment media dubbed Marquez and De Rossi's pairing as "AlEmpoy".

[24] In 2018, Marquez and De Rossi had supporting roles in the ABS-CBN series Since I Found You, which aired from April to August.

[25] That same year, in the comedy film Kusina Kings, Marquez and Zanjoe Marudo starred as a pair of chefs who attempt to save their restaurant by joining a reality show.

[26] Beginning in 2019, Marquez appeared in FPJ's Ang Probinsyano as Domingo "Domengsu" Suarez, an aspiring actor who is mistakenly arrested in a drug raid and later becomes a police informant.

[28] Marquez again co-starred with De Rossi in Walang KaParis, an Amazon Prime Video original film released in March 2023.