Endoscopic mucosal resection is a technique used to remove cancerous or other abnormal lesions found in the digestive tract.
[citation needed] Endoscopic resection with injection of concentrated saline and epinephrine is carried out using a double-channel scope.
Highly concentrated saline and epinephrine are injected (15–20 ml) into the submucosal layer to swell the area containing the lesion and elucidate the markings.
Although all tumors were resected without difficulty, 12.5% developed bleeding (which was managed successfully by endoscopic therapy).
The major complications of endoscopic mucosal resection include postoperative bleeding, perforation, and stricture formation.
During the procedure, an injection of 1:100,000 diluted epinephrine into the muscular wall, along with high-frequency coagulation or clipping, can be applied to the bleeding point for hemostasis.
The largest study of endoscopic mucosal resection by the Australian Consortium included 1000 cases and long term surveillance.
The Mayo Clinic Florida group reported that at least 100 procedures are needed to achieve proficiency.
[4] Many centers in the United States now offer high-quality, high-volume colorectal endoscopic mucosal resection.