Newbury was a 52-gun third rate Speaker-class frigate built for the navy of the Commonwealth of England at Limehouse, and launched in 1654.

She was named for the Parliamentarian victories at the two battles of Newbury.

She spent some time carrying the flag of the senior captain of Prince Rupert's white (van) squadron, commanded by Robert Holmes.

By 1677 her armament had been increased to 62 guns, though she was condemned in 1678, and presumably broken up.

This article about a ship of the line of the United Kingdom is a stub.