Enissa Amani (Persian: انیسا امانی; born 8 December 1981 in Tehran, Iran) is an Iranian-German comedian, artist and activist.

In 2020 she created, produced, and hosted a show about racism called "Die beste Instanz" which led her to win the prestigious German Grimme Online Preis.

She is regularly invited by politicians to hold speeches such as on the Frankfurt Römerberg for Black Live Matter in 2020 and Woman Life Freedom in 2022.

Since 2019 she started doing English standup and had shows in the Soho Theatre in London and appearances at the Laugh Factory Los Angeles, and the Comedy Cellar New York.

In March 2024, to commemorate the 65th anniversary of International Women's Day, Amani was one of a number of female celebrities had their likeness turned into Barbie dolls.