He worked first in Lyon and in 1620, he became valet of the Queen Mother Marie de' Medici and court lutenist in Paris.
In 1631, he retired to Nèves and spent the rest of his life there.
His cousin Denis Gaultier published a printed lute book in 1669, which contained compositions by Ennemond as well.
However, these works had a great influence on the development of lute music of the following years.
Among his most famous works are Le Tombeau de Mezangeau (Allemande), La Belle Homicide (Courante) or Les Canaries du Vieux Gaultier, which became cornerstones of the repertoire of the French Baroque lute.