Enno Louis grew up in the Netherlands, France and Switzerland and had an expensive education.

Quickly after this he tried and executed the favourite and lover of his mother, the geheimrat Johann von Marenholz.

He attempted to become Reichsfürst (Prince) and with the help of the East Frisian scholar Hermann Conring and 15,000 guiders he succeeded in this goal in 1654.

He was engaged with Henriette Catherine of Nassau but eventually married in 1656 with Juliana Sophia of Barby-Mühlingen.

With her he had two daughters, Juliane Louise and Sophie Wilhelmine, who became the third wife of Christian Ulrich I, Duke of Württemberg-Oels.