From 1997 to 2004, she worked as a finance and business associate at Mintz, Levin, Cohn, Ferris, Glovsky, and Popeo.

She rejoined the USTDA as CFO and acting director at the start of the Biden administration.

[3] On October 14, 2021, President Joe Biden nominated Ebong to be the director of the USTDA.

Hearings were held before the Senate Foreign Relations Committee on her nomination on December 14, 2021.

Ebong was confirmed by the entire United States Senate on March 31, 2022, via voice vote.