[2] In Turkey, enoxolone is used in a "Anzibel" lozenge in combination with benzocaine (a local anesthetic) and chlorhexidine hydrochloride (an antibacterial).

Cortisol has intrinsic mineralocorticoid properties (that is, it acts like aldosterone and increases sodium reabsorption) that work on ENaC channels in the collecting duct.

[citation needed] The increased amounts of cortisol binds to the unprotected, nonspecific mineralocorticoid receptors and induce sodium and fluid retention, hypokalaemia, high blood pressure, and inhibition of the renin-angiotensin-aldosterone system.

[12] When R is an anionic NHCO(CH2)CO2K side chain, the sweetening effect is found to be 1200 times that of sugar (human sensory panel data).

In addition, the sweetener molecule requires three proton donor positions, of which two reside at the extremities, to be able to interact efficiently with the receptor cavity.

[citation needed] Both glycyrrhetinic acid and carbenoxolone have a modulatory effect on neural signaling through gap junction channels.

Acetoxolone, the acetyl derivative of glycyrrhetinic acid, is a drug used in the treatment of peptic ulcer and gastroesophageal reflux disease.