[1][2] He made his professional debut in the Mexican League in 1983 as a catcher for the Tecolotes de Nuevo Laredo, where he played for seven seasons.

He won the 2005 Mexican League championship with the Tigres de la Angelópolis and has been named as Manager of the Year three times: in 2003, 2005 and 2012.

[11] In October that same year, Reyes led Mexico to win the 2018 U-23 Baseball World Cup defeating Japan in the final.

[15] In June 2023, Reyes was appointed manager of the Mexican national team for the 2023 Central American and Caribbean Games, leading them to win the gold medal after finishing the tournament with a 5–1 record.

[16][17][18][19] Later that year, he led Mexico to a bronze medal at the 2023 Pan American Games contested in Santiago, Chile, from 18 to 28 October.