Spending the years of World War II assisting the Allied Forces, she returned to Panama and served as the Secretary of the Ministry of Social Welfare, Labor and Public Health until 1950.

In 1922, she became one of the founders of the Feminist Renewal Center Foundation (Spanish: Fundación del Centro Feminista Renovación),[1][4] which aimed to reform the socio-economic and political spheres of Panamanian women.

The following year, the center led the way for the creation of the National Feminist Party, by Clara González and founding members included Morales, Otilia Arosemena de Tejeira [es], Elida Campodónico, and Sara Sotillo.

[1] As superintendent, Morales coordinated charitable activities of institutions which received state subsidies and through her initiative successfully created school lunch rooms, prenatal and postnatal clinics, and free pharmacies.

Morales was awarded the medal Pro Ecclesia et Pontifice by Pope Pius XI for her dedication to Catholic causes and public service and remained as Red Cross Superintendent until 1940.

Returning to Panama, she was elected as president of the Ladies Federation of Catholic Action and the following year in 1945, she worked with the Feminine Patriotic League to encourage women to utilize their newly attained right to vote.