Compared to its contemporary African American paper in Omaha, the Afro-American Sentinel, it focused less on faith and culture, and had a more cautious view of war.

[2] Sections of the paper included stories from others, personal news, church notices, and regular columns such as those by civil rights activist W. H. C. Stephenson and minister John Albert Williams.

[A][4] It contained fewer serialized pieces of fiction than its contemporary African American paper in Omaha, the Afro-American Sentinel, and focused less on faith.

[B][6] It supported the Spanish–American War, but some of its writers believed at the same time that intervention in Cuba would result in the importation of the American color line.

[11] John Albert Williams, who had contributed columns to the Enterprise before its closure, felt it was important to establish another African American paper for Nebraskans; he began publishing the Mission Monitor beyond his church audience as a result.