Eodelphis, from eo- (dawn) and [Di]delphis (a genus of Opossum), thus meaning "dawn opossum",[1] is a genus of stagodont metatherians from the Late Cretaceous of North America, with distinctive crushing dentition.

Named species include E. browni[2] and the more advanced E. cutleri.

Both come from the Late Campanian (Judithian "Land Mammal Age") of Dinosaur Provincial Park, Alberta.

E. cutleri is related to the Maastrichtian genus Didelphodon as indicated by its enlarged premolars and more robust jaw.

[3] Eodelphis was probably an aquatic predator like its relative Didelphodon, and may have weighed about 0.6 kg (1.3 lb), making it one of the largest mammals of its time.