Epena is spoken on the Pacific coastal rivers of the departments of Nariño, Cauca, and Valle del Cauca in Colombia.

A major grouping of the Epena is found in Cauca along the Saija River and three of its major tributaries: the Guangüí, Infí, and Cupí.

Social contact and intermarriage with the neighboring Wounaan is commonplace.

[2] Glottal stops are represented with hyphens.

This article related to the Indigenous languages of the Americas is a stub.