The Ephraim Fitz-Randolph House is a historic house located at 430 S. Randolphville Road in the Randolphville section of Piscataway in Middlesex County, New Jersey.

Built in 1825, it was documented by the Historic American Buildings Survey in 1936.

[3] The house was added to the National Register of Historic Places on March 14, 1973, for its significance in architecture.

[4] Benjamin F. Randolph, originally Fitz-Randolph, emigrated from England in 1684.

His son Moleson settled in Middlesex County.