The Kennedy Space Center and Walt Disney World are located within the diocese.

The diocese includes 15 counties, as follows: Brevard, Citrus, Hardee, Highlands, Indian River, Lake, Okeechobee, Orange, Osceola, Marion, Polk, Seminole, St. Lucie, Sumter and Volusia.

On January 29, 2000 at the 31st Convention of the Diocese, held in Orlando, the delegates approved a new vision for the diocese which called for the revitalization of existing congregations and the establishment of 15 new congregations between 2001 and 2010.

The diocese comprises five deaneries: Central, Northeast, Northwest, Southeast, and Southwest.

Besides managing 7 retirement homes, 4 prep-schools, and 20 day schools the diocese has the following facilities: