His authentication of a newly-discovered Shakespeare First Folio in 2014 garnered a lot of attention, in the wake of which The Washington Post called him "the Robert Langdon of the Shakespearean world".

Rasmussen wrote the annual review of editions and textual studies for Cambridge University Press's Shakespeare Survey from 1999 to 2010.

A review in The New York Times observed that "two eminent Shakespeareans, Jonathan Bate and Eric Rasmussen, have applied modern editing techniques and recent scholarship to correct and update the First Folio".

The book also gathered various mixed reviews including one in Shakespeare Quarterly stating that the "claims made about the project, with respect to both the text and the RSC, are not persuasive.

[7] In 2011, Rasmussen published his book The Shakespeare Thefts: In Search of the First Folios, which was reviewed as "light and lively" and "a highly accessible read".

[8] Another review stated that "the author also provides a terrific appendix, which readers should not skip, that tells how Elizabethans printed books and how the First Folio came to be.

[15] In 2014, Rasmussen along with Lars Engle published the book, Studying Shakespeare's Contemporaries: A Guide to the Major Plays of the Renaissance.