Wilkerson lettered in football and track all four years for the Cleveland Central Catholic High School Ironmen.
[3] Wilkerson played for the Kent State Golden Flashes from 1985 to 1988, recording career totals of 3,830 yards and 36 touchdowns on 739 rushing attempts.
[2][5] Wilkerson was selected to play in the East-West Shrine Game following his senior season.
[15][16] Wilkerson was selected by the New York/New Jersey Knights of the World League of American Football in the 1991 WLAF Draft.
He also tied for the league lead with eleven total touchdowns after recording seven rushing and four receiving scores.
[17] Wilkerson played for the Cleveland Thunderbolts in 1993, recording five tackles, one pass breakup and one interception.